Publications in Scientific Journals:
S. Pichlmair, K. Mereiter, U. Jordis:
"Synthesis of orthogonally protected 3,8-diazabicyclo[3.2.1]octane-2-carboxylic acid--a versatile building block for the synthesis of cocaine analogues";
An eight-step synthesis of an orthogonally protected 3,8-diazabicyclo[3.2.1]octane I from com. available pyroglutamic acid was developed. The target compd. can be used as a versatile building block for combinatorial synthesis of pharmacol. useful compds. and features a hidden a-, b-, d- and .vepsiln.-amino acid, which can also be seen as an example of a new class of cocaine analogs.
Online library catalogue of the TU Vienna:
Created from the Publication Database of the Vienna University of Technology.